دانشگاه اصفهان پژوهش های علوم شناختی و رفتاری 2251-7642 15 2 2025 08 23 The Relationship between Rejection Sensitivity and Suicide Risk in People with gender dysphoria: The Mediating Role of Depression The Relationship between Rejection Sensitivity and Suicide Risk in People with gender dysphoria: The Mediating Role of Depression 1 8 29479 10.22108/cbs.2025.138733.1973 FA Fereshteh Modirfallah Rad Ph. D. Student of Counseling, Roudhen Branch, Islamic Azad University, Roudhen, Iran. Mandana Niknam . Associate Professor, Department of Psychology and Educational Sciences, Faculty of Human Science, Khatam University, Tehran, Iran Simin Dokht Rezakhani Associate Professor of Counseling Department, Roudhen Branch, Islamic Azad University, Roudhen, Iran. Simin Hosseinian Professor, Department of counselling, faculty of education and psychology, Alzahra University, Tehran, Iran. Journal Article 2024 12 27 In the cultural and traditional context of Iran, individuals identified as gender dysphoria often encounter social ostracization and rejection sensitivity, leading to feelings of injustice, victimhood, and stigmatization, exacerbating suicidal ideation. This research aimed to determine the relationship between experiences of rejection & suicide propensity among people with gender dysphoria, while considering the mediating influence of depressive symptoms. A total of 266 people with gender dysphoria were selected to participate in the study in 2022-2023 using purposive and snowball sampling methods. The data collection instruments included the Beck Suicide Ideation Scale (1979), the Rejection Sensitivity Questionnaire(1996), and the Beck Depression Inventory(1961). Subsequent analysis involved Pearson correlation and structural equation modeling techniques facilitated by SPSS 28 and AMOS 24 software suites. The analysis revealed a statistically significant positive correlation between experiences of rejection and depression with suicidal propensity (<em>p</em> < 0.05). A notable positive correlation emerged between experiences of rejection and depression (r = 0.55; <em>p</em> < 0.05). These variables accounted for 45% of the variance in suicide propensity. The mediating role of depression in the relationship between experiences of rejection and suicidal tendency was substantiated. The empirical insights gleaned from this investigation underscore the importance of addressing the interconnectedness of experiences of rejection with psychological maladies, such as depression, and consequent elevations in suicide risk.<br /> <br />  In the cultural and traditional context of Iran, individuals identified as gender dysphoria often encounter social ostracization and rejection sensitivity, leading to feelings of injustice, victimhood, and stigmatization, exacerbating suicidal ideation. This research aimed to determine the relationship between experiences of rejection & suicide propensity among people with gender dysphoria, while considering the mediating influence of depressive symptoms. A total of 266 people with gender dysphoria were selected to participate in the study in 2022-2023 using purposive and snowball sampling methods. The data collection instruments included the Beck Suicide Ideation Scale (1979), the Rejection Sensitivity Questionnaire(1996), and the Beck Depression Inventory(1961). Subsequent analysis involved Pearson correlation and structural equation modeling techniques facilitated by SPSS 28 and AMOS 24 software suites. The analysis revealed a statistically significant positive correlation between experiences of rejection and depression with suicidal propensity (<em>p</em> < 0.05). A notable positive correlation emerged between experiences of rejection and depression (r = 0.55; <em>p</em> < 0.05). These variables accounted for 45% of the variance in suicide propensity. The mediating role of depression in the relationship between experiences of rejection and suicidal tendency was substantiated. The empirical insights gleaned from this investigation underscore the importance of addressing the interconnectedness of experiences of rejection with psychological maladies, such as depression, and consequent elevations in suicide risk.<br /> <br />  https://cbs.ui.ac.ir/article_29479_10fd810a33e4df9542d9d04aae7dafda.pdf